Computational Scientist

About the job

**Job Title: Computational Scientist

Job Location: South San Francisco, California, 94080 (Onsite)

Contract Duration: 12 months with possible extension

Key Responsibilities:

Multimodal perturbation datasets are becoming increasingly large and available, and understanding which data contribute most to model performance is an increasingly important question.

The Regev lab has generated a large multimodal perturbation dataset.

The contractor will train and evaluate models on this data to characterize how different portions of the dataset contribute to model learning, and will evaluate model performance and model outputs against experimental data.

Contract Highlights:

Full time, 40 hours per week, for an initial term of 12-months.

Ownership of a clearly scoped, business-critical workstream with defined deliverables.

Direct collaboration with the project lead and access to an established, documented analysis codebase and cluster compute.

Work with some of the most talented people in the biotechnology industry.

Required Education:

PhD in a computational discipline, or equivalent research experience

Preferred majors: Computational Biology, Computational Sciences, Statistics or Machine Learning

Required skills:

Training and evaluating deep learning models in PyTorch, including designing and executing controlled train/test split experiments on a SLURM cluster.

Strong applied statistics

Proficient scientific Python (numpy, pandas, scanpy/anndata) and reproducible, documented analysis practice.

Preferred Qualifications:

Experience with single-cell transcriptomics

Experience with analysis of CRISPR perturbation screens (perturb-seq or similar).

Familiarity with representation learning

Familiarity with image analysis**